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2017年8月10日星期四

Treatment of Recurrent CKD After Kidney Transplantation



Kidney Transplantation is the last choice for many patients with chronic Kidney Disease. However, a large number of patients suffer from the recurrent CKD after kidney transplantation.
Why Recurrent CKD happens after Kidney Transplant?
Most patients with CKD usually only think it is the kidney damage which affects their life. However, it is only a part of the fact. Yes, the kidney damage causes many other organs damaged, causing various symptoms and complications, such as cardiovascular disease, high blood pressure, liver failure etc. However, kidney damage is far away from the underlying cause.
Actually, more than 95% kidney diseases is caused by immune disorder. In normal condition, each of us have a group of natural immune system. It works to protect our health by releasing antibodies to kill the bacteria outside.
However, in people with immune disorder, the immune system fails to release enough or functional antibodies. As a result, the antibodies form into a new material called immune complex with the bacteria.
The immune complex is harmful for people and it can flow into any where of the body with the carriage of blood. Once it deposits in the kidneys, it will cause inflammations here, causing kidney damages. Thereby, we say if you only aims to reverse the kidney damage with Kidney Transplant or other treatments, CKD is more likely to come back sooner or later.
How to prevent recurrent CKD after Kidney Transplant?
As mentioned above, only dealing with the kidney damage, such as Kidney Transplant, is not enough to prevent the relapse of CKD. To deal with the immune disorder will be another key.
Immunotherapy is suggested for it helps rebuild the immune system and use the immune system to prevent the deposition of immune complex in the kidneys. In this way, the kidney damage relapse will be reversed from the root .

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