2017年3月25日星期六

Clinical Manifestations of Polycystic Kidney Disease

Polycystic Kidney Disease is usually detected when patients grow up. For patients with Polycystic Kidney Disease, their kidneys may keep be normal or somewhat bigger in their early age. Gradually, with the increase of their age, clinical manifestations are more and more obvious. Well then, what are the common clinical manifestations of Polycystic Kidney Disease?
First of all, with numerous cysts, patients’ kidneys usually appear to be swelling. Their kidneys can be larger than normal kidneys for five to six times. Moreover, the two kidneys of one person can be different in size. For patients with not so serious illness condition, they may need CTMRI to diagnose their disease; however, for these whose disease is serious, just palpation is enough.
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Secondly, dull pain as well as discomfort in belly and back is another clinical manifestation of Polycystic Kidney Disease. This kind of clinical manifestation arises from enlargement of cysts and increased strain to renal diolame. Suddenly aggravated pain can always tell bleeding inside cysts or secondary infection of cysts. Blood clot resulted from cyst bleeding or stone may block ureter, casing renal colic thereby.
Thirdly, hematuria which concludes gross hematuria and microscopic hematuria is one of the clinical manifestations of Polycystic Kidney Disease. The root cause of hematuria is the fracture of blood vessels in cyst wall.
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Fourthly, proteinuria and leucocyturia can also occur to patients with Polycystic Kidney Disease. For patients with Polycystic Kidney Disease, their protein in urine usually is less than one gram per day. Compared with proteinuria, leucocyturia is more common.
Fifthly, high blood pressure is the early common manifestation and it has direct relationship with the diagnosis of Polycystic Kidney Disease.
Sixthly, renal damage usually is easy to occur to patients with Polycystic Kidney Disease. However, renal failure seldom appears before patients get thirty years old.
For patients with Polycystic Kidney Disease, their disease develops slowly and the clinical complications usually appear after they step into thirty years old. Polycystic Kidney Disease is genetic disease, hence, it almost is impossible for us to prevent their occurrence, but it is possible for us to delay their appearance.
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