Danger of Protein Urine or Protein Leakage in Kidney Failure

Protein urine is one of the most common symptoms of Chronic Kidney Disease (hereafter referred as CKD). For patients with CKD, the quantity of daily protein loss is more than 3.5g. Then, why doctors and patients pay so much attention on this index? This is because not only that the quantity of protein leakage can be used to estimate about to which degree renal damage has reached, but also that protein leakage can also give rise to various damages to the kidneys and other body organs.How to Manage Protein in Urine for FSGS
In models of renal failure, the deposition of protein in glomerular mesangial areas can be observed. The deposition of micro-molecular substances will lead to mesangial cells damage and proliferation and the increase of mesangial matrix synthetize, which give rise to glomerulosclerosis.Shijiazhuang Kidney Disease Hospital Micro-Chinese Medicine Osmotherapy
Large quantity proteins filtrate through glomerulus into renal tubules, which promotes the activity of lysosome (lysosome can swallow and process nutrient substances like protein). The infiltrations of lysosome into renal tubular cells will surly lead to damages to renal tubules.Micro-Chinese Medicine Osmotherapy
Protein urine gives rise to pathological changes of renal tubular epithelial cells. When protein urine occurs, there exists excessive proliferation of renal cells, which is a kind of abnormal response to invasions. More and more evidences have proven that protein can directly adjust tubular function, change the growing and external expression of tubular cells.Shijiazhuang Kidney Disease Hospital
The reabsorption and metabolism of protein are energy-consuming. This process consumes lot of oxygen, which lead to the occurrence of anomie of tubular cells and as a result the damages to renal cells.Proteinuria and Kidney Disease

Large quantity of protein loss can also lead to lower-concentration of protein in blood or hypoproteinemia. Protein is the most important substance that maintains the blood osmotic pressure. When protein concentration in blood decreases, the osmotic pressure of blood also decreases. Low blood osmotic pressure enhances the filtration of body liquid towards inter-organizational membrane. By this, edema will gradually takes shape.