Nephritic Syndrome is a joint name of kidney disease caused by many factors, with emphasis on glomerular lesion brought about by increasing membrane permeability of glomeruli and lower glomerular filtration rate. It is not a sole disease. The characteristic clinical manifestations are amounts of Proteinuria, lower albuminemia, severe edema, and hyperlipemia, namely " three highs and one lower"
1.Amounts of proteinuria.Proteinuria and Kidney Disease
When mechanical barrier and electric charge barrier are broken, the permeability of plasma protein increase, and amounts of plasma protein leak out of blood. When the quantity of plasma protein is more than that of absorption ability of renal tubules, it will produce a large number of Proteinuria. Those factors can aggravate Proteinuria which can increase the blood perfusion and high filtration of glomeruli, for instance, hypertension, plasma objection and high protein intake.Stem Cell Therapy Treats Kidney Disease
2.Sereve edema.Facial Edema in Nephrotic Syndrome and Bilateral Pedal Edema with Diabetic Nephropathy
Lower albuminemia makes blood concentration lower than that of tissue fluid. So water flows into tissue space from blood. This is the main reason of edema.
3.Hyperlipemia
This symptom is commonly accompanied with lower albuminemia, hypercholesterolemia or hypertriglyceridemia
4.Lower albuminemia.About Shijiazhuang Kidney Disease Hospital
a.Great lose of protein in urine.
b.Part of albumin is degraded by epithelial cells of renal tubules in primary urine, namely about 10g/day.
c.Although the compensation of kidneys can increase the formation of protein, it can't still be equal to the lose and degradation of protein.
d.The edema of Gastrointestinal mucosa leads to poor appetite. Less intake and lose of protein worsens lower alnuminemia.
With these four characteristic clinical symptoms, patients can know whether they suffer from Nephrotic Syndrome generally. If unfortunately they get, they can receive timely treatment and avoid worsening disease. about this aspect, if have any other questions, you can consult our online experts or send e-mail to me
