2015年3月7日星期六

Traditional Western Therapy for CKD

CKD is usually considered as immuno-disease by western doctors. The abnormal immuno-reactions of the body result in sediment of immune complexes onglomerulus, which causes damages to glomerulus. By this, inflammatory cells existed in blood will be induced to infiltrate in these glomerulus and release inflammatory factors that are harmful to renal inherent cells. The decline of renal functions subsequently gives rise to such clinical manifestations as proteinuria (Proteinuria and Kidney Disease), hematuresis, swelling and so on. So, western doctors generally use immunosuppressant like glucocoticoids and cytotoxicdrugs to fight against inflammation.These drugs are effective in preventing the formalization of immunocytes and restricting the functions of mature immunocytes. But for those immunocytes that do not participate in immuno-response, they will avoid the hunt of these drugs and become sensitive to the antigens. Thus , when the same antigen re-emerges, robust inflammatory response of these immunocytes will be something of certainty. This is why the usage of immunosuppressant can take effect quickly but fails to prevent the relapse of CKD.

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