2015年2月13日星期五

What is Chronic Kidney Disease (CKD)

Chronic Kidney Disease (CKD) is a progressive loss in renal function over a period of months or years. Generally Chronic Kidney Disease (CKD) is featured by three factor, namely, damages to kidney lasts for more than three months, and abnormal index exists in urine and blood test as well as in imaging studies of kidney , with glomerular filtration rate being less than 60ml/min. The symptoms of worsening kidney function are unspecific, and may include feeling generally unwell and experiencing a reduced appetite. Often Chronic Kidney Disease (CKD) is diagnosed as a result of screening of people known as to be at risk of kidney problems, such as those with high blood pressure or diabetes. Chronic Kidney Disease (CKD) may also be identified when it leads to one of its recognized complication, such as cardiovascular and anemia(Anemia and Kidney Disease).
Chronic kidney disease is identified by a blood test for creatinine(High Creatinine Levels). Higher levels of creatinine indicate a falling glomerular filtration rate and as a result a decreased capability of the kidneys to excrete waste products.
Creatinine levels may be normal in the early stages of Chronic Kidney Disease (CKD) and the condition is discovered if urinalysis shows that the kidney is allowing the loss of protein or red blood cells into the urine.
To fully investigate the underlying causes of kidney damage, various medical imaging, blood tests and often a kidney biopsy are employed to find out if there is reversible cause of kidney malfunction.

As I have mentioned above, in the early stage, symptoms related to the decline of kidney function are still unobvious, and this is because that renal cells have great complement ability. What is more, kidney fibrosis progress has not been launched in this stage and the damages to kidney are generally reversible. However, without effective and timely treatment, Chronic Kidney Disease (CKD) can easily progress in to Chronic Kidney Insufficiency or Kidney Failure.

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