Wish the patients with kidney disease a happy Christmas day ahead of time

2015年1月9日星期五

One of the Causes of Chronic Kidney Disease (CKD)-- Hypertension

How Hypertension Causes Chronic Kidney Disease (CKD)?
One of the renal functions is to filtrate the internal toxin and prevent the exudation of protein and hemocyte. Hypertension means that blood pressure increases, which lead to the exudation of protein. Once the protein exudates, it will result in the damage of filter screen, which leads to the vicious circle. If it lasts for long time, the renal compensation will increase until kidney failure comes earlier, which can not be reversed.That’s why proteinuria(Proteinuria and Kidney Disease) is more frightening than hematuresis.
Except keeping the blood pressure normal, patients have to pay attention to the following points:
Change Diet habit. One has to have a good diet habit.Hypertension patients have to have low-salt diet, less than 3g/day. But they have to not eat high-potassium food to lower the blood pressure, for potassium can accumulate in body due to lack of urination, which may lead to arrhythmia, even cardiac arrest. And they should have limited high-fat food such as peanuts, fat and soybeans etc.
One of the Causes of Chronic Kidney Disease (CKD)-- Hypertension
As Chronic Kidney Disease is not easily detected in the early stage, only 7% Chronic Kidney Disease (CKD) patients know they have this disease. Hypertension, diabetes and metabolic syndrome have become the main causes of Chronic Kidney Disease. In China, the morbidity of hypertension among adults is 18.8%, its 50% among people over 65; the percentage of hypertension patients with stage III Chronic Kidney Disease is 30% among people over 70 in America. Compared with hypertension, hypertension accompanied by Chronic Kidney Disease is complicated to be treated and the disability and mortality is higher, which raises a concern home and abroad.
Hypertension patients have higher rate of Chronic Kidney Disease (CKD). The morbidity of ESRD among Level 3 hypertension patients is 12 times than people with normal blood pressure. The older hypertension patients are, the higher morbidity of Chronic Kidney Disease (CKD) is. The morbidity of CKD is about 30% among people over 70, which is 2.5 times than that among hypertension patients at the age of 60-69, 20 times than that among people 40-59 years old, and 2-3times among people at the same age without diabetes and hypertension. Therefore, one has to attach more importance to Chronic Kidney Disease (CKD). Early detection is the key to do early diagnosis and treatment, which is helpful to delay the arrival of ESRD and reduce the mortality and disability rate.
To treat it by lower the blood pressure

As the Chronic Kidney Disease caused by hypertension has relationship with arteriosclerosis, we have to strictly control blood pressure to control the development of arteriosclerosis. It is found in UKPDS experiment that when the SBP>110mmHG, the rate of capillaries complication is increasing; when SBP>125 mmHg, the risk of myocardial infarction is sustainably increasing. The MAP has to be controlled under 100mmHg and BP under 130/80 mmHg to effectively control the development of renal arteriosclerosis. If the protein is >1 g/d, the blood pressure goal should be 125/75mmHg. If patients can tolerate it, the SBP goal should be≤120 mmHg .

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