Renal anemia is a secondary anemia and it can be manifested as the occurrence of the following several pathological changes.
● Reducing of Red Blood Cells.
Decrease of erythropoietin can result in the reducing of red blood cells. Moreover, imbalanced trace elements, vitamin and nutritional deficiency as well as the effects of inhibiting factor to erythropoiesis all these can result in the reducing of erythropoietin，as a result, red blood cells reduce.
● Shortened Life Span of Red Blood Cells.
With excretion and secretion functions, our kidneys can on one side excrete metabolic products and toxins, on the other side excrete erythropoietin. Owing to renal damage, our kidneys can not excrete sufficient erythropoietin, as a result, red blood cells reduce. In addition, due to renal damage, toxic substances produced by our body can not be excreted smoothly through our kidneys, causing accumulation of them in our body. Toxic substances can affect the metabolism of red blood cells and thus shorten the life span of red blood cells.
● Great Loss of Red Blood Cells
We all know some patients with Chronic Kidney Disease have hematuria which results from the existence of great amount of red blood cells in urine. Great loss of red blood cells can also cause anemia. Renal anemia is easy to be ignored at the first. Due to the unobvious symptom, Chronic Kidney Disease is hard to be found in the early stage. Therefore, renal anemia usually is misdiagnosed as other types of anemia. Renal anemia has a close relationship with renal damage. In most of the cases, patients with Chronic Kidney Disease have renal anemia and sometimes, renal anemia also is the dominant symptom.
Renal anemia is not an independent disease, but a symptom of kidney disease. It is the major manifestation of primary kidney disease and Chronic Renal Insufficiency. Therefore, if we want to remove renal anemia, we must treat kidney disease first.
