More than 4,000 noxious chemical compound produced by each cigarette is likely to enter the lung and then to be one part of the blood circulation. As we know, kidneys should filter and excrete the wastes of the body, so the aromatic amines (tar for instance) and acrolein in the cigarette also should be expelled out of the body via kidneys, during which, the kidneys will be damaged a lot.
◆ Being the main cause of craving of tobacco, nicotine in the cigarette (0.5-2.7 mg/cigarette) is a kind of strong excitant which can stimulate the nervous centralis and refresh oneself. Meanwhile, nicotine can help to increase the heart rate as well as the blood pressure, and then leading to cardiovascular disease. The blood coagulation leaded by it is a reason for the blocking of the vessels which can decrease the blood volume in the kidneys and exacerbate Chronic Kidney Diseases.
◆ In addition, the carbon monoxide (CO) in the cigarette (400ppm/per cigarette) is a kind of toxin which can interfere the exchange of the oxygen without color and smell, and it can also impede the combination of the oxygen and protoheme by resulting in anoxia in the body. In a normal person, the CO in the blood should be less than 1%, but that in a smoker may be as high as 15%. If this condition lasts for long, the blood can be blocked and influence the mind and our judgment; further more, the accumulation of the fat makes the renal burden heavier than before.
◆A long-term smoking makes the blood pressure changeable, and the blood vessels uptight, which can broke the Immunotherapy microcirculation gradually. As for the patients with kidney disease, smoking is not only a destroyer of the blood circulation and oxygen supply, but also a causer of cancer, includes Renal Cell Carcinoma, Transitional Cell Carcinoma, Carcinoma of Urinary Bladder. Smoking is closely related to the data of renal damage, especially the decrease of GFR and appearance of proteinuria. That is why the patients with Chronic Kidney Disease should be more cautious if they are smokers.
