2014年10月20日星期一

The Dangerous Factors Increasing the Risk of Cerebrovascular Disease--the Complication of CKD

The statistics shows that the mortality related to cerebrovascular disease is 12.7% among CKD patients receiving dialysis. Cerebrovascular disease is one of the common complications of CKD as well as the main death cause of uremia patients.
Since that CKD patients tend to have cerebrovascular disease, then what are the symptoms CKD patients should pay attention to?
First, hypertension is the most dangerous factor for CKD patients. It is common that CKD patients often have hypertension, arteriosclerosis, especially cerebrovascularsclerosis at the same time. Therefore, CKD patients with hypertension are apt to have cerebrovascular disease.
The second one is something about the renal function. It is found that high serum creatinine patients, with or without hypertension, have high risk of cerebrovascular disease.
MAU is also one of causes of stroke. MAU refers to the albumin in urine is beyond the expected arrange but under the urine proteins examinable in the Urine Routine Examination, i.e. urine albumin 30-300mg/d/24h. when CKD patients have MAU,they obviously have higher risk of cerebrovascular disease, stroke, renal damage and mortality.
If CKD patients are accompanied by anemia, the risk of stroke is increasing. When the renal function declines, the number of hemopoietin decrease, which reduces the protective function of neurons and increases the risk of stroke.
Hyperur icemia is anther factor. It may be caused by hypoxia of some tissues when the kidney lacks blood supply.

Diabetes is one of the main causes of CKD. The morbility of cerebrovascular disease is high among Diabetic Nephropathy patients.

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