Proteinuria is a common symptom for many patients with chronic kidney
disease. When chronic kidney disease patients find out that they have
proteinuria, they do not feel pain or itch, which will not lead to
inconvenience, either. However, the most characteristic of proteinuria is that
it is refractory. No matter people take western medicine or Chinese medicine,
they will get trapped into the recurrent proteinuria. Why?(Proteinuria and Kidney Disease)
Firstly, the proteinuria which appears in patients with chronic kidney
disease can be divided into two kinds: one is renal glomerular proteinuria and
the other is renal tubular proteinuria. In normal condition, when the blood
flows through the renal glomeruli, the protein will not leak out into renal
tubules due to the size and the charge of protein. Only a little can leak out
into renal tubules and most of them will be reabsorbed into renal tubules.
Generally, the amount is less than 150mg. As for youngsters, the index can be a
little high but generally it can research as high as 250mg/24 hours.
Why does proteinuria come into being? It is due to the damage of renal
glomerular filtration barrier. Once the renal intrinsic cells are damaged, or
the matrix is damaged, the function of filtration will also be influenced, so
the excessive amount of protein will leak out into renal tubules and then is
discharged out of the body together with urine. The reabsorption ability of
renal tubules can not afford it so a large amount of protein leaks out, thus
forming renal proteinuria. The renal tubular proteinuria occurs because the
renal epithelial cells are damaged, which leads to the damage of absorption
ability. The protein in the original urine can not be reabsorbed, which can also
lead to the discharge of the protein. Generally speaking, the pathogenesis of
the two types are similar, both of which are due to the not repairing of the
renal intrinsic cells.
