The first symptom of Diabetic Nephropathy is proteinuria. At first, filtration pressure increases and the electric charge in the filtration membrane changes, both of which lead to the occurrence of albumin in the urine, which is called selective proteinuria. There is no increased globulin. This condition can last for many years. With the increase of filtration pore of the renal glomerular basilar membrane, big molecules can pass through. With the disease develops, protein in urine turns continuous and serious protein in urine. If the protein in urine is more than 3g per day, the prognosis will no be good. The condition may develop progressively until they develop into Nephrotic Syndrome.
The second symptom of Diabetic Nephropathy is edema. In the early stage, patients can not feel edema. Some have slight edema before the plasma protein decreases. When the protein in urine is more than 3g within 24 hours, edema will appear. Obvious edema can be seen among those whose Diabetic Nephropathy develops fast.
The third symptom of Diabetic Nephropathy is high blood pressure, which is very common in patients with Diabetic Nephropathy. As a matter of fact, most serious kidney disease can cause high blood pressure, and in turn, high blood pressure can also worsen kidney disease. All in all, controlling blood pressure is very important.
The fourth symptom of Diabetic Nephropathy is renal failure. Once patients suffer from Diabetic Nephropathy, the course is progressive. And it not controlled well, azotaemia and even uremia will take place.
The fifth symptom of Diabetic Nephropathy is anemia(Anemia and Kidney Disease). Patients with serious azotaemia will have slight or moderate anemia. Chalybeate can not achieve satisfactory effect. Anemia is due to the barrier of red blood cell production. It may be related to the long time limitation of protein diet and azotaemia.
The last symptom of Diabetic Nephropathy is such as diabetic retinopathy, which is often accompanied with Diabetic Nephropathy.
Since we have known about the symptoms of Diabetic Nephropathy, we should take effective measures in time so as to avoid further damage.
