2014年8月20日星期三

Drug Therapy in Chronic Kidney Disease

What is the drug therapy in chronic kidney disease? Generally, in traditional treatment, immune medicines which are used to treat chronic kidney disease can be divided into three kinds:
The first one which focuses on cellular immunity is such as FK506, Sirolimus, and Cyclosporin A. The second kind of medicine which focuses on body fluid is Leflunomide. The third one which focuses on various sources of immunosuppressive (agent) is such as glucocorticoid, cyclophosphamide, chlorambucil, methotrexate, azathioprine, Mycophenolate Mofetil and so on.
However, every coin has two sides. Long time using these drugs can lead to many side effects. They either treat chronic kidney disease excessively or moderately, which leads to a fact that at last, patients can not help being trapped by uremia.
So what is the new therapy which can bring patients with chronic kidney disease new hope? As we mentioned in the above passages that about 95% of the chronic kidney disease is immune disease except PKD and so on. So the treatment of chronic kidney disease should focus on the immune blocking, immune tolerance, immune protection, and immune treatment in order.
Besides these, we should also realize that kidney is a complicated organ. Once trapped by the suffering of chronic kidney disease, it is not easy for patients to recover. So it is necessary and important to keep calm. Secondly, chronic kidney disease patients should also get prepared to treat chronic kidney disease for a long time. The inflammation in kidney is immune inflammatory reaction, which is autologous inflammation disease. It is a natural reaction, which is also super allergic reaction. If the abnormal things which remain in the kidney can not be cleaned out completely, the inflammatory reaction will not stop. Western medicine has no good drugs for solving it. Chinese medicine can be effective, but it needs time. So patients with chronic kidney disease should prepare in mind that it is a long time.

In addition, stop the bad habit as soon as possible such as do not keep warm in winter, which can lead to cold and worsen the kidney disease. Just as we mentioned in the above, chronic kidney disease is due to the deposition of immune complex. When patients get a cold, antigen and antibody will combine and new immune complex will come into being, which will increase the burden. So developing a good habit is also very important to assure the effect of the treatment.

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