Wish the patients with kidney disease a happy Christmas day ahead of time

2014年5月25日星期日

CKD Stage 1 Stage 2 and Iceberg Theory

In this passage, we will introduce CKD Stage 1 Stage 2 together with iceberg theory. When some people who are in good condition and have never suffered from a disease before go to have a physical examination in a hospital for the first time, they can even be diagnosed with uremia, which is a big surprise. Why?
Here, we have to introduce iceberg theory first. It is said that one eighth of an iceberg is above the water. All of the rest is underneath the water. It is first put forward by Freud, a neurologist and Hemingway, a novelist in America. This theory can be applied in many fields such as management, medical field, and so on.
When some normal people go to have a physical examination in a hospital for the first time, they can be diagnosed with kidney disease. Among them, two third of them have developed into renal insufficiency and one fourth of them have developed into uremia stage. Why? Just as what iceberg theory said, when kidney disease patients start to feel symptoms or discomfort, the pathological damage inside of the kidney has already been serious. It is because of the compensation ability of the kidney. That is also why when a person donates a kidney, he can also survive.
So timely physical examination and prevention in daily life become important. How can we carry it out?
We should figure out two points:
Who should have such examination?
Which examinations should they take?
Generally, the factors which can lead to chronic kidney disease are such as age, diabetes, high blood pressure, and family history, etc.
How long should the above mentioned people take physical examinations?
Firstly, those who are healthy can have examination once a year.
Secondly, those who have already had high blood pressure or diabetes should have renal function test and urine test at least twice a year.
Thirdly, those who have had symptoms should go to hospital as early as possible and have a syImmunotherapyatic examination.
Fourthly, if the renal function declines rapidly, people should find out the potential and reversible causes and adopt effective treatment.
Which examinations should people take?
Generally, the examinations include urine test, MAU, protein in 24 hours, blood sugar, blood fat, and so on.
What shall we do in our daily life so as to prevent CKD?
For healthy people, they should pay attention to the following points:
1. limit the intake of salt.
2. have regular physical examination
3. control the body weight
4. prevent cold.
5. stop smoking and alcohol
6. avoid taking in medicine freely

For the high risk groups, besides the above mentioned, they should also control diabetes, high blood pressure, urea acid, obesity, and hyperlipidemia, etc.

Relation between eGFR and CKD

Some patients with chronic kidney disease (CKD) are confused about the relation between eGFR and CKD. As a matter of fact, eGFR equals GFR. GFR is short for glomerular filtration rate, which is the most scientific index which can test kidney function. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. In many countries, chronic kidney disease patients attach much importance to serum creatinine, considering it as an important reference. However, internationally, creatinine is not as scientific as eGFR, for serum creatinine can be influenced by many other factors such as food which they take in, exercise, and even infection such as catching a cold or flu.
According to eGFR (GFR), chronic kidney disease can be divided into 5 stages. The normal range of eGFR (GFR) is 80 to 120 mL/min/1.73m2. In addition, the index of GFR will decrease by 1 every year after persons are 40 years old. We can also say that the older we are, the lower the normal index of GFR will be.
In stage 1, the GFR is more than 90 mL/min/1.73m2.
In stage 2, the GFR is between 60 to 89 mL/min/1.73m2. In this stage, there is no symptom in clinic and the serum creatinine is also normal for the compensation ability of kidney. When there are some damaged kidney glomeruli, other heathy ones will do more work to finish the filtration. So the level of serum creatinine is normal in this stage. We can also say that, this stage is compensation stage.
In stage 3, the GFR is between 30 to 59 mL/min/1.73m2. This stage can also be called discompensation stage for the healthy kidney glomeruli will also be damaged due to long time excessive work.
In stage 4, the GFR is between 15 to 29 mL/min/1.73m2. At this time, patients come into renal failure stage, which indicates the function of kidney become to decline.

In stage 5, the GFR is less than 15, which means that patients with chronic kidney disease have come into uremia stage, or advanced stage of renal failure.

Can Patients with Lupus Nephritis Conceive

Can patients with Lupus Nephritis conceive? This is a question which most young ladies with Lupus Nephritis are concerned about. Generally, they are not suggested to be pregnant. The risks they put forward are as follows:
Firstly, pregnancy will influence the fetus a lot, which may even lead to abortion and premature birth, giving sorrow to the family members as well as the lady. There is a statistics that the abortion rate is as high as 23.7 and the premature rate is as high as 30%.
Secondly, when lady with Lupus Nephritis are pregnant, the two kidneys will function for two persons, which will lead the kidney to work more and even suffer from more pressuring. In this case, protein in urine may be more. And hematuria will also appear or worsen. What’s worse, during this process, blood pressure will become high as well with the deterioration of kidney function.
Thirdly, the medicine lady with Lupus Nephritis are took in during pregnancy or conceiving will do harm to the fetus as well, especially the western medicine. There will be chemical reaction in ladies’ body if they take in western medicine.
If ladies with Lupus Nephritis have had been pregnant, what should they pay attention to or be aware of?
1. If ladies find out that their blood pressure increases, they should treat it or stop pregnancy.
2. Monitor the growth of the fetus. If fetus are found to have been trapped in the mother’s body, mothers should stop conceiving.
3. Have enough sleep and diet. Proper diet can decrease the recurrence of Lupus Nephritis. Enough rest can also avoid the activity of Lupus Nephritis.
As for the treatment, ladies with Lupus Nephritis are suggested to have immune therapy, for lupus is a kind of self-immune disease. In Shijiazhuang Kidney Disease Hospital, the immune therapy can be divided into six steps: scientific diagnosis, immune inhibition, immune tolerance, immune adjustment, immune protection and immune clearance.
When should they consider conceiving?
1. After the treatment, all the levels turn normal such as proteinuria, hematuria, blood pressure and so on.

2.Half a year after ladies stop the medicine, they can consider having a baby. Although they stop the medicine, the drug which accumulated in the body can also do harm to the body. So half a year later, it will be OK.

How to Increase Kidney Function

How to increase kidney function? When kidney is damaged and patients develop into kidney failure stage, kidney function will also be influenced. How to increase it becomes a topic which chronic kidney disease patients are concerned about. As we mentioned in the previous articles, about 95% of kidney diseases are connected with immune. So aiming at conquering kidney disease and increasing kidney function, we develop into immune treatment according to the kidney disease caused by immune. As long as the kidney disease is treated, kidney function will be increased accordingly.
Firstly, after a Immunotherapyatic and scientific treatment, patients come into immune inhibition stage. In Shijiazhuang Kidney Disease Hospital, we researched out an immune inhibition therapy, which can also be called rapid inhibition of immune inflammatory reaction. It is aimed at the inhibition of inflammatory reaction. The reason why it can achieve the effect is as follows: On one hand, we have a diagnosis syImmunotherapy, which can help us analyze the type of immune reaction and the place where the immune complex deposits. On the other hand, we have the most advanced medicine and technology. We communicate and cooperate with advanced countries.
Secondly, patients come into immune tolerance stage. Why? After immune inhibition, immune reaction has been stopped. However, there are still damaged cells and immune complex in the kidney, which will cause a series of further immune response. So we put forward immune tolerance theory. After that, chronic kidney disease patients will inject medicine which is used to inhibit the immune reaction so as to prevent further immune reaction.
Thirdly, patients come into immune adjustment stage. Our body will not allow immune complex to stay in the body for a long time, for it does not belong to kidney at all. So we should not only tolerate, but also take effective measures to adjust, which means that we clear the immune complex making full use of Micro-Chinese Medicine for it can promote the blood circulation, including micro-blood circulation and dissolve the stasis of blood, which western medicine can not achieve.
Fourthly, patients come into immune protection stage. There have been damaged intrinsic cells in the kidney. To protect them, we use some medicine which can repair the damaged intrinsic cells and enhance the immune ability, thus reviving renal function and increase kidney function.

The above mentioned are about how to increase kidney function in our hospital. For more information, please consult us online or leave a message.

Why Can Immunotherapy Treat Diabetes

At present, Immunotherapy is widely used in clinic to treat a variety of diseases. Recently, news that Immunotherapy can treat diabetes is a heat topic, which is also proves in clinic.
In most of time, Immunotherapys which is applied in clinic is collected from human beings, which can differentiate into kinds of cells for it is initial cells and can repair the damaged cells, as well as increase the immune ability in human beings.
How does Immunotherapy treat diabetes? The mechanism goes as follows: pancreas islet β cells are damaged, which leads to insufficient secretion of insulin. In this case, the blood sugar will increase. If this can not be treated or controlled well, it will lead to syImmunotherapyatic disorder and a series of complications will occur as well. Immunotherapy can repair the damaged pancreas islet β cells, thus recovering the function of insulin. In this case, the secretion of insulin can turn normal and diabetes can recover consequently.

In Shijiazhuang Kidney Disease Hospital, it is usually applied together with Micro-Chinese Medicine Osmotherapy, the effect of which is much better for Micro-Chinese Medicine can provide a cleaner environment for the growth of Immunotherapy. If you still have any questions, please feel free to consult us or leave a message.

Stages of Chronic Renal Failure in China

Generally, chronic kidney failure in China can be divided into 4 stages: compensation stage of renal insufficiency, discompensation stage of renal insufficiency, early stage of renal failure, advanced stage of renal failure, the basis of which is the level of serum creatinine. The detailed information is as follows:
In the compensation stage, serum creatinine is 133 to 177umol/L. In this stage, patients generally have no symptoms, or they can only feel weakness, soreness of the waist, and increased urine at night.
In the discompensation stage, serum creatinine is 186 to 442 umol/L. In this stage, patients feel poor appetite, slight anemia and slight acidosis.
In the early stage of renal failure, serum creatinine is 450 to 707 umol/L. In this stage, the above mentioned symptoms become more obvious.
In the advanced stage of renal failure, serum creatinine is more than 707 umol/L. In this stage, patients begin to have heart failure, high K, bleeding in digestive tract, barriers in nervous centralis, and so on, which even threatens patients’ life.
In addition, the stages of chronic kidney failure in China can also be connected with the classification of CKD internationally, which is on the basis of GFR (glomerular filtration rate).
Generally, the compensation stage equals the second stage of CKD.
The discompensation stage equals the third stage of CKD.
The early stage of renal failure equals the fourth stage of CKD.

The end stage of renal failure equals the fifth stage of CKD.

2014年5月16日星期五

Chronic Kidney Disease Aggravates Cardiovascular Disease

The death rate of those people who have Chronic Kidney Disease (CKD) and cardiovascular disease together is 10~30 times higher than that of common people. An epidemic research demonstrates that 8% of people (esp. senior citizens) have chronic renal insufficiency. Among them, cardiovascular diseases are the most common complications, and the heavier the renal insufficiency is, the higher the morbidity of cardiovascular disease will be.
Traditional influencing factors such as Hypertension, Hyperlipidemia, Diabetes and smoking still indicate a poor prognosis among sufferers with Chronic Kidney Disease. Moreover, the influence of high blood pressure on sufferers with Chronic Kidney Disease may be much higher. They often have an elevated homocysteine, oxidative stress, disordered lipid metabolism, increased inflammation markers, and abnormal metabolism of calcium and phosphorus, which reduce the smoothness of blood vessels so as to promote the formation of atherosclerosis.
In the development process, diabetes sufferers always have Chronic Kidney Disease. Clinical cases illustrate that when Diabetic Nephropathy sufferers have micro-albumin in their urine, they are always accompanied with uncontrolled glucose, high blood pressure, carotid artery incrassation and other types of coronary disease. The death rate of those who have micro-albumin urine together with diabetes is higher than that of those who have no micro-albumin urine. They are very likely to die from myocardial infarction, apoplexy or other cardiovascular diseases, because they have more risk factors such as obstructed function of endothelium, abnormal fibrinolysis coagulation syImmunotherapy and inflammation. Also, micro-albumin urine may indicate renal insufficiency.
The morbidity of myocardosis among sufferers with Chronic Kidney Disease is also very high. High blood pressure and atherosclerosis lead to the incrassation of left ventricular. In addition, Anemia and arteriovenous fistula can cause excessive volume load. These abnormal changes in heart structure will arouse obstruction in ventricle, with heart failure and myocardial ischemia as its clinical manifestations. In particular, those people who are undergoing dialysis often have Hypertension or Hypotension because of water and sodium retention. Heart failure is the manifestation of severe cardiovascular disease and is a risk factor for a poor prognosis.

Cardiovascular Disease is a most common and serious complication of Chronic Kidney Disease. In order to prevent cardiovascular diseases, Chronic Kidney Disease should be treated effectively and fundamentally to remit the risk factors in causing cardiovascular diseases.

How to Prevent Cardiovascular Disease?

There are many reasons for the high morbidity and death rate of cardiovascular disease which is a serious complication of Chronic Kidney Disease. Chronic Kidney Disease and proteinuria itself are risk factors. In addition to the unmodifiable reasons such as age and gender, smoking, bad diet habit, Anemia, malnutrition, uncontrolled glucose, etc. are all have great influence on the occurrence of cardiovascular disease.
Here are some tips for sufferers with Chronic Kidney Disease to prevent cardiovascular disease.
★ Fall into the habit of healthy diet.
Improper diet is closely related to the occurrence of cardiovascular disease, so keeping a healthy diet is of great importance in daily life. In detail, (1) Fine grains should be accompanied with coarse grains, and coarse grains which contain dietary fiber and Vitamin B is a good choice and should be taken with a proper amount. (2) Meat and vegetables are all indispensable. Meat contains protein and fat, while vegetables contain vitamins and other nutrient content. Sufferers with Chronic Kidney Disease should limit the intake of protein, and the protein they have should be taken from eggs, milk and lean meat, which can guarantee the supply of amino acid and have no pressure on kidneys. (3) Pay attention to the total amount of salt and edible oil.
★ Keep a good living habit.
Most of all, smoking and cigarette should be get rid of. Secondly, keeping a regular exercise with low intensity is very helpful, and strenuous exercises are not suggested to do. Another very important point is to avoid nervous and fluctuated emotion. Last but not least, protection of cold is really important especially when temperature changes sharply, because sharp vasodilatation and vasoconstriction can arouse the acute cardiovascular disease.
★ Consult doctors regularly.
Despite of all the factors such as age and the stage of disease, or even when the amount of urinary protein is quite small, those sufferers with ensured Chronic Kidney Disease should pay much attention to risk factors including waistline, blood pressure and proteinuria. Meanwhile, some factors that are related to Chronic Kidney Disease such as Anemia and metabolism of calcium and phosphorus should be treated positively. At last, some medicines should be used to treat kidney disease as well as prevent cardiovascular diseases.

However, if you want to get a fundamental treatment for Chronic Kidney Disease and its complications, only taking medicines cannot be adequate. Micro-Chinese Medicine Osmotherapy and Immunotherapy are all effective treatment which has been proved by thousands of successful cases in clinic. Only when Chronic Kidney Disease is well controlled, can complications like cardiovascular diseases be prevented in advance. If you want to learn more about our treatment, please visit Micro-Chinese Medicine Osmotherapy.

Three Complications of Chronic Nephritis

Chronic Nephritis, Chronic Glomerulonephritis as another name, is a kind of Chronic Kidney Disease, which mainly refers to the glomerular damage. Chronic Kidney Disease can cause many damages on various organs; similarly, Chronic Nephritis can give rise to many complications.
Renal Anemia
● When renal units are damaged, our kidneys can not play their functions smoothly. Glomerulus has function of filtration, and when they are damaged, they can not filter out excessive water and electrolyte, leading to the occurance of anemia and abnormal function of platelet, lymphocyte as well as obstacles of clotting syImmunotherapy. Among these changes, anemia is the most serious one.
● Infection
For patients with Chronic Nephritis, their immunity is poorer than that of healthy people. Long-term proteinuria means the greatly loss of protein, which will lead to malnutrition and disorder of immunologic function. Patients with Chronic Nephritis are easy to get respiratory tract infection, urinary tract infection and skin infection. These infections are difficult to treat and after getting infection, patients may have no obviously symptoms. As malignant incitant, respiratory tract infection, urinary infection and skin infection always trigger the acute attack of Chronic Nephritis, which will aggravate the illness condition.
● High Blood Pressure.
Chronic renal insufficiency usually gives rise to serious cardiovascular complications such as high blood pressure, atherosclerosis, myocardosis, pericarditis and renal insufficiency. The major cause of these complications is the abnormal metabolism. According to the statistics, the incidence of high blood pressure reaches as high as seventy percent to eighty percent. Nearly all the patients who have to receive renal replacement therapy have high blood pressure. Among these patients, low-salt diet and dialysis can decrease the blood pressure effectively for three quarters of them. However, for the rest patients, their blood pressure increases after they do dialysis.

The appearance of these complications means that patients’ disease is aggravated, so patients with Chronic Nephritis should receive treatment as soon as possible.

Renal Anemia Caused by Chronic Kidney Disease

Renal Anemia refers to the Anemia which appears when various kinds of chronic kidney disease (CKD) develops into renal failure, and among them, the one caused by chronic renal failure is always the most serious one. Many patients go to hospital just because the Anemia and then are detected with chronic kidney disease.
When serum creatinine rises up to 309μmol/L (3.5mg/dL), most of the patients get Anemia, which aggravates chronic kidney disease further. There are many cause of the Anemia, including:
1. The amount of EPO, which is secreted by kidney, decreases.
2. There are some substances in blood that can restrict the function of red blood cells.
3. The lifespan of red blood cells declines.
4. There is lack of ferrum and folacin, and malnutrition also occurs.
5. Blood losing due to bleeding or blood drawing.
6. Hyperparathyroidism.
7. Secondary infection.
8. Aluminium poisoning.
The following presentations are helpful for the diagnosis of renal Anemia.
◆ Renal dysfunction, and serum creatinine is up to 309μmol/L (3.5mg/dL), accompanying with electrolyte disturbance and acid base imbalance.
◆ The simple renal Anemia always presents normal cells, but if there is ferrum and folacin deficiency, hypochromic microcytic Anemia will appear.
◆ In most cases, white blood cells and blood platelet are still normal, but the quantity of neutrophil drops.
◆ Red blood cell count and megakaryocyte are normal.
◆ The time of ferrum disappearance is normal or longer, the rate of conversion of ferrum is normal or lower, the use ratio of ferrum drops, the content of ferrum in serum is normal or higher.
◆ The content of serum folacin is lower, but in the red blood cells normal.
◆ EPO in serum become less, and general anti-anemia medicine has no effect.

Chronic kidney disease often leads to Renal Anemia, and renal Anemia exacerbates chronic kidney disease further at the same time. Many patients in clinic go to hospital just because of Anemia, and then they are detected with chronic kidney disease. Renal Anemia aroused by Polycystic kidney disease (PKD) or Hypertensive Nephropathy is somewhat slighter, but the one aroused by nephrectomy, and chronic kidney disease accompanied with Nephrotic Syndrome or serious hyperparathyroidism is usually severer. If you have any related question, leave a message.

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