2014年4月17日星期四

What Are the Causes of Elevated Creatinine Levels

What are the causes of elevated creatinine level? Creatinine is a metabolism product from muscles. The creatinine is dischareged out of the body through renal glomerular filtration membrane. In the renal glomerular filtration membrane, there are small pores, through which, creatinine can come out into urine. Normally, the serum creatinine is 44 to 103umol/L.
Once kidney or renal glomerular filtration membrane is damaged, creatinine will not discharge out. So serum creatinine becomes high. And creatinine in urine becomes low. Actually, in normal condition, creatinine level in urine should be higher than the level of serum creatinine.
And normally, secrum creatinine level will not rise even kidney is damaged, which is because kidney has a strong ability of compensation. When some glomeruli are damaged, other healthy glomeruli can replace and do more work, which leads the serum creatinine to stay in normal condition. So once serum creatinine rises, it means that the damage is more than 50% in the kidney.
So once we have found out that the serum creatinine is high, even a little high, we should attach importance on it. Besides this, the following factors can also lead to the elevated serum creatinine.
1. People who have renal insufficiency can have temporarily elevated serum creatinine due to infections such as cold, urinary infection, etc.
2. People lost a lot of water due to fever, sweat, less amount of water intake, etc, which leads to the less blood flow in the kidney, thus causing temporary elevated serum creatinine.
3. People who have had kidney disease take in medicine which does harm to the kidney, which will also lead to the elevated serum creatinine. It can be reversible.
4. The relapse of kidney disease can also lead to the elevated serum creatinine as well.

5. Due to fatigue, not enough rest, etc, elevated serum creatinine can also take place.

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