Is there any relationship between Hypertension,Diabetes, Blood Clots and CKD,
this article will give you answers.
As we all know, approximately 26 million American adults have chronic kidney
disease – and millions of others are at risk, but may not know it. Kidney
disease is often called the “silent killer,” because it has no symptoms until
the advanced stage of the disease. In fact, 1 in 9 Americans has chronic kidney
disease, but many are unaware that they have it, because they do not feel
ill.
Causes of CKD
Primary causes are two very common conditions: diabetes and high blood
pressure. Many health conditions can contribute to CKD, but the primary causes
are two very common conditions: diabetes and high blood pressure. Diabetes and
the accompanying high levels of blood sugar can damage the organs in the body,
including the kidneys and heart. High blood pressure, or hypertension, can
damage blood vessels throughout the body, including those in the kidneys. When
these blood vessels are damaged, the kidneys are less effective at removing
waste and extra fluid from the body. The excess fluid, in turn, raises blood
pressure even more, which then increases the risk of chronic kidney disease – a
vicious cycle. Sometimes, chronic kidney disease may progress to kidney failure,
requiring dialysis or kidney transplantation.
Effects of CKD
People with chronic kidney disease are at greater risk of developing blood
clots. Mount Sinai researchers found in two studies that people with chronic
kidney disease (CKD) develop blood clots much faster than healthy adults, and as
CKD gets worse, so do the blood clots. They also found people with CKD and
diabetes had more pathologic features of high-risk atherosclerotic plaque in
their arteries than people with diabetes alone.
"We knew that chronic kidney disease increased risk for the development of
adverse cardiovascular events such as heart attacks or strokes, but our study is
among the first to show that CKD substantially increases clot strength and the
rate at which clots develop," said Usman Baber, MD, Assistant Professor of
Medicine at Mount Sinai School of Medicine. "These results demonstrate a
significant need to closely monitor the tens of millions of Americans with CKD
to reduce the risk of a cardiovascular event."
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