In CKD stage 3, there will appear many symptoms such as high blood pressure,
proteinuria, pain in the lower back, etc. Besides these, hematuria or blood
urine is also concerned by many patients, which can be divided into gross
hematuria and microscopic hematuria. We can see gross hematuria with our naked
eyes. The urine looks reddish, which is like water where flesh is washed. We can
only see microscopic hematuria with the help of microscopy. There are more than
3 red blood cells per high power field.
Gross hematuria can vary widely in appearance, from light pink to deep red
with clots. Despite the quantity of blood in the urine being different, the
types of conditions that can cause the problem are the same, and the workup or
evaluation that is needed is identical.
What are the causes of blood in urine?
The causes of gross and microscopic hematuria are similar and may result from
bleeding anywhere along the urinary tract. One cannot readily distinguish
between blood originating in the kidneys, ureters (the tubes that transport
urine from the kidneys to the bladder), bladder, or urethra.
Here, we mainly research renal hematuria, which means that blood urine is
caused by the damage of kidney. In kidney, there is renal glomerular filtration
membrane, through which, only small molecules such as creatinine, urea nitrogen
and urea acid, etc can leak out. When kidney is damaged, there is also damage in
this filtration membrane, thus causing the leaking out of red blood cell, the
urine of which is caused hematuria or blood urine.
In stage 3 of chronic kidney disease, hematuria or blood urine comes into
being like this. If not treated well, the leaking out of red blood cells will
worsen blood urine in turn, which forms a vicious circle for the pore of basilar
membrane will become bigger.
